细胞生物学
先天免疫系统
水通道蛋白
生物
植物免疫
转录因子
植物对草食的防御
质外体
生物化学
拟南芥
细胞壁
基因
突变体
受体
作者
Mou Zhang,Haotian Shi,Ningning Li,Nana Wei,Yan Tian,Jinfeng Peng,Xiaochen Chen,Liyuan Zhang,Meixiang Zhang,Hansong Dong
出处
期刊:Plant Physiology
[Oxford University Press]
日期:2021-12-23
卷期号:188 (4): 2325-2341
被引量:36
标识
DOI:10.1093/plphys/kiab604
摘要
To overcome pathogen infection, plants deploy a highly efficient innate immune system, which often uses hydrogen peroxide (H2O2), a versatile reactive oxygen species, to activate downstream defense responses. H2O2 is a potential substrate of aquaporins (AQPs), the membrane channels that facilitate the transport of small compounds across plasma membranes or organelle membranes. To date, however, the functional relationship between AQPs and H2O2 in plant immunity is largely undissected. Here, we report that the rice (Oryza sativa) AQP OsPIP2;2 transports pathogen-induced apoplastic H2O2 into the cytoplasm to intensify rice resistance against various pathogens. OsPIP2;2-transported H2O2 is required for microbial molecular pattern flg22 to activate the MAPK cascade and to induce the downstream defense responses. In response to flg22, OsPIP2;2 is phosphorylated at the serine residue S125, and therefore gains the ability to transport H2O2. Phosphorylated OsPIP2;2 also triggers the translocation of OsmaMYB, a membrane-anchored MYB transcription factor, into the plant cell nucleus to impart flg22-induced defense responses against pathogen infection. On the contrary, if OsPIP2;2 is not phosphorylated, OsmaMYB remains associated with the plasma membrane, and plant defense responses are no longer induced. These results suggest that OsPIP2;2 positively regulates plant innate immunity by mediating H2O2 transport into the plant cell and mediating the translocation of OsmaMYB from plasma membrane to nucleus.
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