重症监护医学
病危
医学
败血症
严重败血症
体外
重症监护室
阿尔法德罗曲菌素
随机对照试验
感染性休克
外科
出处
期刊:Blood Purification
[S. Karger AG]
日期:2022-01-01
卷期号:51 (12): 990-996
被引量:7
摘要
The potential for treatment of the critically ill using blood purification techniques has been discussed for several decades. However, since the first attempts at applying extracorporeal techniques to patients with sepsis were described, there has been considerable hesitancy towards the widespread adoption of such methods, given the lack of mortality benefit observed and indeed the paucity of randomized controlled studies. However, this is not unique so far as studies on the critically ill are concerned where there is a dearth of studies providing a positive finding to influence clinical practice. Consequently, as well as targeted patient selection, it is perhaps time to consider endpoints other than mortality in studies on the critically ill, particularly in blood purification studies where, to-date, such heterogeneous groups of patients have been studied.
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