The effectiveness and biosafety of diatrizoate contrast media in complicated cholelithiasis.

医学 胃肠病学 内镜逆行胰胆管造影术 相伴的 胰腺炎 中毒性肝炎 内科学 造影剂 泛影酸酯 放射科 肝炎
作者
Dmytro Osadchuk,О. И. Карел,І. М. ДЕЙКАЛО,Halina Falfushynska
出处
期刊:PubMed 卷期号:50 (296): 102-108 被引量:1
链接
标识
摘要

Adverse reactions after intravascular administration of iodine-based contrast media are well-known. Nevertheless the same type of contrast media is also used for endoscopic retrograde cholangiopancreatography and systemic absorption of contrast media after mentioned procedure routinely occurs, not much is known about effects of widely used diatrizoates (Triombrast) on the hepato-pancreato-biliary system in case of cholelithiasis treatment.The aim of the present study was to determine the effectiveness and biosafety of diatrizoate contrast media in terms of complicated cholelithiasis healing using conventional and improved surgery treatment protocols based on set of biochemical markers.The paper presents materials of clinical observation and biochemical analysis of 122 patients have been diagnosed with gallstone disease complicated by choledocholithiasis and cholangitis and biliary pancreatitis. Biochemical liver tests before and after surgery treatment using conventional and improved protocols were determined.Biochemical manifestations of hepatocellular injury included exceeded activity of γ-glutamyltranspeptidase and aminotrasferases as well as level of liver fatty acid-binding protein and bilirubin which were different between groups of patients with cholelithiasis who suffered from concomitant cholangitis and pancreatitis. Proposed management algorithm for patients with gallstone disease with concomitant cholangitis and pancreatitis links to get rid of endoscopic retrograde cholangiography with contrast agent from the conventional surgery treatment protocols because its most obvious downside.Patients with gallstone diseases revealed significant biochemical changes that should be successfully resolved after surgery treatment without endoscopic retrograde cholangio- pancreatography with contrast media because its hepatotoxic effect.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
白斯特发布了新的文献求助10
刚刚
1秒前
1秒前
wxs发布了新的文献求助10
1秒前
CR7完成签到,获得积分10
3秒前
桐桐应助pipi采纳,获得10
3秒前
David发布了新的文献求助10
3秒前
4秒前
galvin完成签到,获得积分10
5秒前
旧城以西发布了新的文献求助10
5秒前
芽芽配茄子完成签到 ,获得积分10
5秒前
量子星尘发布了新的文献求助30
5秒前
田様应助悦耳的尔冬采纳,获得10
6秒前
6秒前
草莓大王完成签到,获得积分10
7秒前
哈哈哈完成签到,获得积分10
7秒前
7秒前
7秒前
可乐发布了新的文献求助10
7秒前
姚景涛完成签到,获得积分10
7秒前
你说的完成签到 ,获得积分10
8秒前
9秒前
11秒前
11秒前
12秒前
Sor完成签到,获得积分10
13秒前
凌儿响叮当完成签到 ,获得积分10
13秒前
14秒前
15秒前
Sor发布了新的文献求助10
15秒前
Qizhang发布了新的文献求助10
16秒前
qiyun发布了新的文献求助10
17秒前
在水一方应助文艺的白翠采纳,获得10
17秒前
呼呼呼完成签到,获得积分10
18秒前
xkw发布了新的文献求助10
19秒前
lee完成签到,获得积分10
19秒前
22秒前
赵君峰完成签到,获得积分10
22秒前
YG发布了新的文献求助10
22秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3970048
求助须知:如何正确求助?哪些是违规求助? 3514739
关于积分的说明 11175783
捐赠科研通 3250115
什么是DOI,文献DOI怎么找? 1795198
邀请新用户注册赠送积分活动 875630
科研通“疑难数据库(出版商)”最低求助积分说明 804951