A new library of 1,2,3‐triazole based benzofuran scaffolds: Synthesis and biological evaluation as potential antimicrobial agents

Abstract A library of new 1,2,3‐triazole based benzofuran derivatives was constructed via synthesizing them through the Rap‐Stoermer reaction in moderate to good yields. Various reaction conditions were examined to develop an optimized synthetic route for affording the desired products in good yields. All the synthesized compounds were characterized by 1 H‐NMR, 13 C‐NMR, FT‐IR, and mass spectral data. The title compounds were screened in vitro for their potential antimicrobial properties and most of the compounds exhibited promising antimicrobial activities.