Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

遗传学生物髓系白血病表观遗传学髓样医学 DNA甲基化癌症研究基因白血病生物信息学计算生物学免疫学基因表达

作者

T J Ley,Christopher A. Miller,Li Ding,Benjamin J. Raphael,Andrew J. Mungall,Gordon L. Robertson,Katherine A. Hoadley,Timothy J. Triche,Peter W. Laird,Jack Baty,Lucinda Fulton,Robert S. Fulton,Sharon E. Heath,Joelle Kalicki-Veizer,Cyriac Kandoth,Jeffery M. Klco,Daniel C. Koboldt,Krishna Kanchi,Shashikant Kulkarni,Tamara Lamprecht,David E. Larson,Ge Lin,Charles Lu,Michael D. McLellan,Joshua F. McMichael,Jacqueline E. Payton,Heather K. Schmidt,David H. Spencer,Michael H. Tomasson,John W. Wallis,Lukas D. Wartman,Mark A. Watson,John S. Welch,Michael C. Wendl,Adrian Ally,Miruna Balasundaram,İnanç Birol,Yaron S.N. Butterfield,Readman Chiu,Andy Chu,Eric Chuah,Hye Jung E. Chun,Richard Corbett,Noreen Dhalla,Ranabir Guin,Anyuan He,Carrie Hirst,Martin Hirst,Robert A. Holt,Steven J.M. Jones,Aly Karsan,Darlene Lee,Haiyan I. Li,Marco A. Marra,Michael Mayo,Richard A. Moore,Karen Mungall,Jeremy Parker,Erin Pleasance,Patrick Plettner,Jacquie Schein,Dominik Stoll,Lucas Swanson,Angela Tam,Nina Thiessen,Richard Varhol,Natasja Wye,Yongjun Zhao,Stacey Gabriel,Gad Getz,Carrie Sougnez,Lihua Zou,Mark D.M. Leiserson,Fabio Vandin,Hsin Ta Wu,Frederick R. Applebaum,Stephen B. Baylin,Rehan Akbani,Bradley M. Broom,Ken Chen,Thomas Motter,Nguyễn Công Khanh,John N. Weinstein,Nianziang Zhang,Martin L. Ferguson,Christopher M. Adams,Aaron Black,Jay Bowen,Julie M. Gastier‐Foster,Thomas W. Grossman,Tara M. Lichtenberg,Lisa Wise,Tanja M. Davidsen,John A. Demchok,Kenna Shaw,Margi Sheth,Heidi J. Sofia,Liming Yang,James R. Downing,Greg Eley,Shelley Alonso,Brenda Ayala,Julien Baboud,Mark Backus,Sean P. Barletta,Dominique Berton,Anna L. Chu,Stanley Girshik,Mark A. Jensen,A Kahn,Prachi Kothiyal,Matthew Nicholls,Todd Pihl,David Pot,Rohini Raman,Rashmi N. Sanbhadti,Eric E. Snyder,Deepak Srinivasan,Jessica Walton,Yunhu Wan,Zhining Wang,Jean‐Pierre J. Issa,Michelle Le Beau,Martin Carroll,Hagop Kantarjian,Steven M. Kornblau,Arnoud Boot,Phillip H. Lai,Hui Shen,David J. Van Den Berg,Daniel J. Weisenberger,Daniel C. Link,Matthew J. Walter,Bradley A. Ozenberger,Elaine R. Mardis,Peter Westervelt,Timothy A. Graubert,John F. DiPersio,Richard K. Wilson

出处

期刊：The New England Journal of Medicine [New England Journal of Medicine]
日期：2013-05-02 卷期号：368 (22): 2059-2074 被引量：4495

链接

nejm.org wustl.edu wustl.edu unc.edu unc.edu europepmc.org europepmc.org nih.gov nih.govdoi.org

标识

DOI：10.1056/nejmoa1301689

摘要

Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. The relationships between patterns of mutations and epigenetic phenotypes are not yet clear.

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Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

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