脱质子化
配体(生物化学)
席夫碱
八面体
化学
金属
过渡金属
苯甲酸
八面体分子几何学
核化学
结晶学
立体化学
晶体结构
有机化学
催化作用
受体
离子
生物化学
作者
Muhammad Iqbal Khan,Ayub Khan,İqbal Hussain,Murad Ali Khan,Saima Gul,Mazhar Iqbal,Inayat-ur-Rahman,Fazli Khuda
标识
DOI:10.1016/j.inoche.2013.06.014
摘要
Six new transition metal complexes derived from the reaction of 4(4-(dimethylamino) benzylideneamino) benzoic acid and Mn(II), Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) cations, were prepared, isolated and characterized by a range of spectral and analytical methods including UV/Vis, FT IR, NMR, MS, powder XRD, TGA and SEM. The complexes were formed with the deprotonation of the ligand and presented typical six-coordinated octahedral geometry. In addition, the biological activity was evaluated by conducting in vitro anti-bacterial, anti-fungal and anti-leishmanial screenings. All the complexes were found more active than the ligand, while complex 7 revealed biological significance.
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