子痫
医学
血流动力学
滋养层
胎儿
胎儿生长
宫内生长受限
怀孕
内科学
心脏病学
胎盘
生物
遗传学
作者
A. Dall’Asta,M. Minopoli,Ruben Ramirez Zegarra,E. di Pasquo,T. Ghi
摘要
Abstract Pre‐eclampsia and fetal growth restriction (FGR) have been long related to primary placental dysfunction, caused by abnormal trophoblast invasion. Nevertheless, emerging evidence has led to a new hypothesis for the origin of pre‐eclampsia and FGR. Suboptimal maternal cardiovascular adaptation has been shown to result in uteroplacental hypoperfusion, ultimately leading to placental hypoxic damage with secondary dysfunction. In this review, we summarize current evidence on maternal cardiac hemodynamics in FGR and pre‐eclampsia. We also discuss the different approaches for antihypertensive treatment according to the hemodynamic phenotype observed in pre‐eclampsia and FGR.
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