An Overview of Palladium-Catalyzed N-alkylation Reactions

-Alkylation of amines is a vital reaction in the synthesis of numerous bioactive compounds and materials. Among transition metals, palladium has emerged as a particularly effective catalyst for these transformations. The unique advantages of palladium arise from its superior catalytic efficiency, ability to operate under mild conditions, high selectivity and recyclability. Additionally, palladium facilitates the borrowing hydrogen methodology, offering sustainable and environmentally friendly alternatives. This review covers advancements in palladium-catalyzed