Palladium-Catalyzed Decarboxylative Domino Synthesis of Fused Quinolin-2(1H)-one Scaffolds Containing Perfluoroalkyl Unit

A novel palladium-catalyzed domino radical cyclization and C-H activation/decarboxylation of 1,7-enynes with o-bromobenzoic acids and perfluoroalkyl iodides has been developed for the expedite construction of fused perfluoroalkyl-containing quinolin-2(1H)-one scaffolds. This...