A Comparison of Gout Flares with the Initiation of Treat‐to‐Target Allopurinol and Febuxostat: A Post‐hoc Analysis of a Randomized Multicenter Trial

Initiating urate-lowering therapy (ULT) in gout can precipitate arthritis flares. There have been limited comparisons of flare risk during the initiation and escalation of allopurinol and febuxostat, administered as a treat-to-target strategy with optimal anti-inflammatory prophylaxis.