作者
Myriam Chalabi,Y.L. Verschoor,Pedro Batista Tan,Sara Balduzzi,Anja U. van Lent,Cecile Grootscholten,Simone Dokter,Nikè V.J.A. Büller,Brechtje A. Grotenhuis,Koert F.D. Kuhlmann,Jacobus W. Burger,Inge L. Huibregtse,Tjeerd S. Aukema,Eduard R. Hendriks,Steven J. Oosterling,Pétur Snæbjörnsson,Emile E. Voest,Lodewyk F.A. Wessels,Geerard L. Beets,Monique E. van Leerdam,Ton N. Schumacher,José G. van den Berg,Geerard L. Beets,John B.A.G. Haanen
摘要
Mismatch repair-deficient (dMMR) tumors can be found in 10 to 15% of patients with nonmetastatic colon cancer. In these patients, the efficacy of chemotherapy is limited. The use of neoadjuvant immunotherapy has shown promising results, but data from studies of this approach are limited.