免疫性血小板减少症
单克隆抗体
CD38
免疫学
抗体
医学
免疫系统
病毒学
生物
干细胞
川地34
遗传学
作者
Yunfei Chen,Yanmei Xu,Huiyuan Li,Ting Sun,Xuan Cao,Yuhua Wang,Feng Xue,Wei Liu,Xiaofan Liu,H. Dong,Rongfeng Fu,Xinyue Dai,Wentian Wang,Yueshen Ma,Zhen Song,Ying Chi,Mankai Ju,Wenjing Gu,Xiaolei Pei,Renchi Yang,Lei Zhang
标识
DOI:10.1056/nejmoa2400409
摘要
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by autoantibody-mediated platelet destruction. Treatment with CM313, a novel anti-CD38 monoclonal antibody, can result in targeted clearance of CD38-positive cells, including plasma cells.
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