A Facile Procedure to Halodecarboxylation of Hydroxyaromatic Carboxylic Acids

With readily available NXS (X = Cl, Br) as sole promoter in ethyl alcohol at room temperature without any other catalysts or additives, an efficient approach to directly halodecarboxylation of hydroxyaromatic acid was reported. This environmentally friendly route tolerated wide substrate scope with good to excellent yields under convenient condition.