医学
立场文件
短肠综合征
肠外营养
小儿胃肠病
专家意见
梅德林
肝病学
肠功能衰竭
系统回顾
重症监护医学
普通外科
儿科
家庭医学
外科
病理
政治学
法学
作者
Lorenzo Norsa,Olivier Goulet,Daniele Alberti,Barbara DeKooning,Magnus Domellöf,Nadja Haiden,Susan Hill,Flavia Indrio,Jutta Köglmeier,Alexandre Lapillonne,Verónica Luque,Sissel J. Moltu,O Linderkamp,Francesco Savino,Elvira Verduci,Jiří Bronský
标识
DOI:10.1097/mpg.0000000000003849
摘要
Short bowel syndrome (SBS) is the leading cause of intestinal failure (IF) in children. The mainstay of treatment for IF is parenteral nutrition (PN). The aim of this position paper is to review the available evidence on managing SBS and to provide practical guidance to clinicians dealing with this condition. All members of the Nutrition Committee of the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) contributed to this position paper. Some renowned experts in the field joined the team to guide with their experience. A systematic literature search was performed from 2005 to May 2021 using PubMed, MEDLINE, and Cochrane Database of Systematic Reviews. In the absence of evidence, recommendations reflect the expert opinion of the authors. Literature on SBS mainly consists of retrospective single-center experience, thus most of the current papers and recommendations are based on expert opinion. All recommendations were voted on by the expert panel and reached >90% agreement. The first part of this position paper focuses on the physiological mechanism of intestinal adaptation after surgical resection. It subsequently provides some clinical practice recommendations for the primary management of children with SBS from surgical resection until discharged home on PN.
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