粘菌素
肺炎克雷伯菌
脑室炎
医学
脑膜炎
抗生素
多重耐药
吸入
微生物学
麻醉
外科
生物
大肠杆菌
生物化学
基因
作者
Xiaona Li,Xinrong Guo,Yangfeng Liu,Rong Chen,Chen Ma,Xiaogang Kang,Fang Yang,Wen Li,Wen Jiang
出处
期刊:Future Microbiology
[Future Medicine]
日期:2023-06-01
卷期号:18 (9): 547-552
被引量:1
标识
DOI:10.2217/fmb-2022-0277
摘要
The management of severe neurologic infections due to multidrug-resistant (MDR) Klebsiella pneumoniae infection remains a challenge. Limited antibiotic treatment regimens make treatment of severe MDR K. pneumoniae infection more difficult. We describe a patient who developed severe meningitis and ventriculitis after craniotomy caused by MDR K. pneumoniae and was effectively treated with the administration of multichannel applications (intravenous, intrathecal and aerosol inhalation) of colistin sulfate. This case provides clinical evidence that the intrathecal, intravenous and aerosol inhalation of colistin sulfate by multichannel application can be a last resort in refractory intracranial infection by MDR K. pneumoniae.
科研通智能强力驱动
Strongly Powered by AbleSci AI