药物治疗
肽
纳米颗粒
药理学
化学
纳米技术
医学
内科学
生物化学
材料科学
作者
Shivani A. Kumar,Rimon Ranjit Das,Surbhi Malik
标识
DOI:10.1002/9781119900931.ch15
摘要
Peptide-nanoparticle conjugates (PNCs) have recently emerged as a promising medicinal tool. Synergy between the two potential kinds of accouterments allows for greater control over their natural actions, exceeding the separate paraphernalia's innate limitations. PNCs have been developed for a variety of functions over the years, including drug delivery, blockage of pathogenic biomolecular relationships, molecular imaging, and liquid vivisection. Here, in this template, we present a thorough overview of the essential sequences and structural features used to create polypeptide self-assembled nanoparticles, direct particles to their target and affect their distribution in cells and tissues, stimulate and regulate cellular response, and stabilize nano-constructs both biologically and physically. This study presents a detailed summary of recent developments in the broad topic of PNCs, as well as a guideline for scientists who are new to the field.
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