The optical frequency comb (OFC) is prospective technique that can hike up the communication carrying capability of wide range in optical fiber communication [1]. Due to its numerous applications, including ultra-short pulse generation for different wavelength [2] multi-wavelength ultra-fast photonic signal processing, high-accuracy optoelectronic detectors and wavelength division multiplexing [3, 4], it draws attention of researchers. A collection of spectral lines is produced by a continuous laser source modulating a radio frequency signal. This manuscript proposed an effective technique for generation of OFC with cascading of modulators with Highly Nonlinear Fiber (HNLF) that produces coherent and highly spectral comb lines.