Relationship of Daily Step Counts to All-Cause Mortality and Cardiovascular Events

医学 内科学 人口 环境卫生
作者
Niels A. Stens,Esmée A. Bakker,Asier Mañas,Laurien M. Buffart,Francisco B. Ortega,Duck-chul Lee,Paul D. Thompson,Dick H. J. Thijssen,Thijs M.H. Eijsvogels
出处
期刊:Journal of the American College of Cardiology [Elsevier BV]
卷期号:82 (15): 1483-1494 被引量:31
标识
DOI:10.1016/j.jacc.2023.07.029
摘要

The minimal and optimal daily step counts for health improvements remain unclear. A meta-analysis was performed to quantify dose-response associations of objectively measured step count metrics in the general population. Electronic databases were searched from inception to October 2022. Primary outcomes included all-cause mortality and incident cardiovascular disease (CVD). Study results were analyzed using generalized least squares and random-effects models. In total, 111,309 individuals from 12 studies were included. Significant risk reductions were observed at 2,517 steps/d for all-cause mortality (adjusted HR [aHR]: 0.92; 95% CI: 0.84-0.999) and 2,735 steps/d for incident CVD (aHR: 0.89; 95% CI: 0.79-0.999) compared with 2,000 steps/d (reference). Additional steps resulted in nonlinear risk reductions of all-cause mortality and incident CVD with an optimal dose at 8,763 (aHR: 0.40; 95% CI: 0.38-0.43) and 7,126 steps/d (aHR: 0.49; 95% CI: 0.45-0.55), respectively. Increments from a low to an intermediate or a high cadence were independently associated with risk reductions of all-cause mortality. Sex did not influence the dose-response associations, but after stratification for assessment device and wear location, pronounced risk reductions were observed for hip-worn accelerometers compared with pedometers and wrist-worn accelerometers. As few as about 2,600 and about 2,800 steps/d yield significant mortality and CVD benefits, with progressive risk reductions up to about 8,800 and about 7,200 steps/d, respectively. Additional mortality benefits were found at a moderate to high vs a low step cadence. These findings can extend contemporary physical activity prescriptions given the easy-to-understand concept of step count. (Dose-Response Relationship Between Daily Step Count and Health Outcomes: A Systematic Review and Meta-Analyses; CRD42021244747)
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
qixiaoqi发布了新的文献求助10
刚刚
博慧完成签到 ,获得积分10
1秒前
小刘医生完成签到,获得积分10
3秒前
安安完成签到,获得积分10
3秒前
啊啊啊啊完成签到,获得积分10
3秒前
英俊的铭应助飞飞鱼采纳,获得10
5秒前
科目三应助zzz采纳,获得10
5秒前
小小西瓜萝卜青菜完成签到,获得积分10
5秒前
思源应助虚幻采枫采纳,获得10
6秒前
6秒前
不安的可乐完成签到,获得积分10
6秒前
7秒前
nano完成签到 ,获得积分10
7秒前
da完成签到,获得积分10
7秒前
科研通AI2S应助啊啊啊啊采纳,获得10
8秒前
cyndi发布了新的文献求助20
8秒前
9秒前
852应助小小西瓜萝卜青菜采纳,获得10
11秒前
sci完成签到,获得积分10
12秒前
醉熏的鑫发布了新的文献求助10
13秒前
Nizarn发布了新的文献求助10
13秒前
14秒前
14秒前
乐呵呵完成签到,获得积分10
14秒前
14秒前
忧心的惜天完成签到 ,获得积分10
14秒前
77完成签到,获得积分10
15秒前
yz发布了新的文献求助10
15秒前
周周南完成签到 ,获得积分10
18秒前
18秒前
zz完成签到,获得积分10
18秒前
自由老头应助cyndi采纳,获得20
19秒前
努力做实验完成签到 ,获得积分10
20秒前
wf发布了新的文献求助10
20秒前
研友_ngkEgn完成签到,获得积分10
20秒前
代丽娟完成签到,获得积分10
20秒前
22秒前
快来下载文献完成签到,获得积分10
22秒前
苹果山芙完成签到,获得积分10
23秒前
煎饼狗子发布了新的文献求助10
23秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds第二卷 1200
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038657
求助须知:如何正确求助?哪些是违规求助? 3576306
关于积分的说明 11375198
捐赠科研通 3306108
什么是DOI,文献DOI怎么找? 1819379
邀请新用户注册赠送积分活动 892698
科研通“疑难数据库(出版商)”最低求助积分说明 815066