非快速眼动睡眠
失眠症
听力学
原发性失眠
睡眠(系统调用)
医学
心理学
多导睡眠图
脑电图
K-络合物
多导睡眠图
慢波睡眠
睡眠阶段
睡眠障碍
麻醉
精神科
计算机科学
操作系统
作者
Andrew D. Krystal,Jack D. Edinger,William K. Wohlgemuth,Gail R. Marsh
出处
期刊:Sleep
[Oxford University Press]
日期:2002-09-01
被引量:324
标识
DOI:10.1093/sleep/25.6.626
摘要
To determine whether the frequency spectrum of the sleep EEG is a physiologic correlate of 1) the degree to which individuals with persistent primary insomnia (PPI) underestimate their sleep time compared with the traditionally scored polysomnogram (PSG) and 2) the sleep complaints in PPI subjects who have relatively long traditionally scored PSG sleep times and relatively greater underestimation of sleep time.We compared EEG frequency spectra from REM and NREM sleep in PPI subjects subtyped as subjective insomnia sufferers (those with relatively long total sleep time and relative underestimation of sleep time compared with PSG), and objective insomnia sufferers (those with relatively short PSG total sleep time) with EEG frequency spectra in normals. We also studied the correlation between these indices and the degree of underestimation of sleep. Further, we determined the degree to which sleep EEG indexes related to sleep complaints.Duke University Medical Center Sleep Laboratory.Normal (N=20), subjective insomnia (N=12), and objective insomnia (N=18) subjects.N/A.Lower delta and greater alpha, sigma, and beta NREM EEG activity were found in the patients with subjective insomnia but not those with objective insomnia, compared with the normal subjects. These results were robust to changes in the subtyping criteria. No effects were found for REM spectral indexes. Less delta non- REM EEG activity predicted greater deviation between subjective and PSG estimates of sleep time across all subjects. For the subjective insomnia subjects, diminished low-frequency and elevated higher frequency non- REM EEG activity was associated with their sleep complaints.NREM EEG frequency spectral indexes appear to be physiologic correlates of sleep complaints in patients with subjective insomnia and may reflect heightened arousal during sleep.
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