纳米技术
生物相容性材料
材料科学
合成生物学
药物输送
工程类
生物医学工程
生物信息学
生物
作者
Fangyu Zhang,Rodolfo Mundaca‐Uribe,Nelly Askarinam,Zhengxing Li,Weiwei Gao,Liangfang Zhang,Joseph Wang
标识
DOI:10.1002/adma.202107177
摘要
There has been considerable interest in developing synthetic micromotors with biofunctional, versatile, and adaptive capabilities for biomedical applications. In this perspective, cell membrane-functionalized micromotors emerge as an attractive platform. This new class of micromotors demonstrates enhanced propulsion and compelling performance in complex biological environments, making them suitable for various in vivo applications, including drug delivery, detoxification, immune modulation, and phototherapy. This article reviews various proof-of-concept studies based on different micromotor designs and cell membrane coatings in these areas. The review focuses on the motor structure and performance relationship and highlights how cell membrane functionalization overcomes the obstacles faced by traditional synthetic micromotors while imparting them with unique capabilities. Overall, the cell membrane-functionalized micromotors are expected to advance micromotor research and facilitate its translation towards practical uses.
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