Myocardium microcirculation study in a healthy Chinese population using 3.0-T cardiac magnetic resonance intravoxel incoherent motion imaging

盒内非相干运动 医学 组内相关 磁共振成像 心室 核医学 灌注 心脏病学 体质指数 微循环 人口 内科学 有效扩散系数 放射科 心理测量学 环境卫生 临床心理学
作者
Shilan Li,Anna Mou,Xin Li,Yan Guo,Qingwei Song,Ailian Liu,Zhiyong Li
出处
期刊:Acta Radiologica [SAGE Publishing]
卷期号:63 (5): 596-605 被引量:1
标识
DOI:10.1177/02841851211006311
摘要

Intravoxel incoherent motion imaging (IVIM) can non-invasively evaluate diffusion and microvascular perfusion.To explore the myocardium microcirculation of a healthy Chinese population by using cardiac magnetic resonance (CMR) IVIM.A total of 80 healthy volunteers (44 men, 36 women) who underwent 3.0-T CMR examination were enrolled. All participants had cardiac cine imaging and short-axis CMR-IVIM of the left ventricle (LV) using multiple b-values. The consistency of the IVIM parameters was assessed by intraclass correlation coefficient (ICC) and the Bland-Altman test. Spearman correlation analysis was performed between IVIM parameters and age, and body mass index (BMI). The differences of IVIM parameters were analyzed between gender and different ages.LV end-diastolic volume (EDV), end-systolic volume (ESV), LVmass, cardiac output (CO), and BMI in the male group were higher than those in the female group (P<0.05). IVIM parameters had good intra-observer and inter-observer consistency (≥0.75). Bland-Altman analysis also showed good intra-observer and inter-observer consistency. ADCfast decreased with increasing female age (rs = -0.37; P = 0.01), while IVIM parameters had no correlation with BMI regardless of sex. ADCfast in the female group had a statistical difference between different age groups. The ADCslow and f in the male group were lower than those in the female group (P<0.05); however, there was no statistical difference in ADCfast between genders.IVIM parameters in healthy Chinese volunteers provided good consistency. There was a negative correlation between ADCfast and age in the female group.
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