提升（金属加工）
尿酸
化学
内科学
生物化学
内分泌学
生物
医学
材料科学
冶金
作者
Anjana Chaudhary,Zhibin He,Daniel Atwood,Makoto Miyazaki,Özgür Akın Oto,A. Davidoff,Charles L. Edelstein
出处
期刊：American Journal of Physiology-renal Physiology
[American Physiological Society]
日期：2024-04-18
卷期号：326 (6): F1004-F1015
被引量：2
标识
DOI：10.1152/ajprenal.00372.2023
摘要
Humans are predisposed to gout because they lack uricase that converts uric acid to allantoin. Rodents have uricase, resulting in low basal serum uric acid. A uricase inhibitor raises serum uric acid in rodents. There were two aims of the study in polycystic kidney disease (PKD):
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