A Domino Decarboxylative Alkylation/Annulation for the Synthesis of Pyrrolo-benzimidazolones

In this study, we report a novel, radical-promoted one-pot synthesis of pyrrolo-benzimidazolone (pyrrolo[1,2-a]benzimidazol-1-ones), involving the reaction of aliphatic carboxylic acids with N-propiolyl-benzimidazole in the presence of ammonium persulfate. A diverse...