Microextraction by packed sorbent: Uncommon detection techniques, sorbents, samples and analytes

Among sample preparation approaches, the most desirable are procedures that ensure high efficiency and reproducibility, that are cheap, fast and simple, that minimize the number of operational steps and that require a small amount of sample and solvent and are thus environmentally friendly. Microextraction by packed sorbent (MEPS) is a miniaturized form of solid-phase extraction, the use of which has been continuously expanding since its introduction in 2004. This technique can be considered green, and due to its many advantages, it has been widely accepted and used for sample pretreatment prior to instrumental analysis. This mini-review deals with the presentation and discussion of atypical, less described approaches and solutions with the MEPS technique, especially in regard to the detection techniques and sorbents used, the samples analyzed and the analytes determined. We hope this review will interest, inspire and motivate readers to explore new MEPS applications.