清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

Heart–Lungs interactions: the basics and clinical implications

预加载 后负荷 医学 心脏病学 冲程容积 内科学 血流动力学 心输出量 麻醉 脉冲压力 血压 心力衰竭 射血分数
作者
Mathieu Jozwiak,Jean‐Louis Teboul
出处
期刊:Annals of Intensive Care [Springer Nature]
卷期号:14 (1) 被引量:1
标识
DOI:10.1186/s13613-024-01356-5
摘要

Abstract Heart–lungs interactions are related to the interplay between the cardiovascular and the respiratory system. They result from the respiratory-induced changes in intrathoracic pressure, which are transmitted to the cardiac cavities and to the changes in alveolar pressure, which may impact the lung microvessels. In spontaneously breathing patients, consequences of heart–lungs interactions are during inspiration an increase in right ventricular preload and afterload, a decrease in left ventricular preload and an increase in left ventricular afterload. In mechanically ventilated patients, consequences of heart–lungs interactions are during mechanical insufflation a decrease in right ventricular preload, an increase in right ventricular afterload, an increase in left ventricular preload and a decrease in left ventricular afterload. Physiologically and during normal breathing, heart–lungs interactions do not lead to significant hemodynamic consequences. Nevertheless, in some clinical settings such as acute exacerbation of chronic obstructive pulmonary disease, acute left heart failure or acute respiratory distress syndrome, heart–lungs interactions may lead to significant hemodynamic consequences. These are linked to complex pathophysiological mechanisms, including a marked inspiratory negativity of intrathoracic pressure, a marked inspiratory increase in transpulmonary pressure and an increase in intra-abdominal pressure. The most recent application of heart–lungs interactions is the prediction of fluid responsiveness in mechanically ventilated patients. The first test to be developed using heart–lungs interactions was the respiratory variation of pulse pressure. Subsequently, many other dynamic fluid responsiveness tests using heart–lungs interactions have been developed, such as the respiratory variations of pulse contour-based stroke volume or the respiratory variations of the inferior or superior vena cava diameters. All these tests share the same limitations, the most frequent being low tidal volume ventilation, persistent spontaneous breathing activity and cardiac arrhythmia. Nevertheless, when their main limitations are properly addressed, all these tests can help intensivists in the decision-making process regarding fluid administration and fluid removal in critically ill patients.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
彦嘉发布了新的文献求助10
2秒前
斯文败类应助ceeray23采纳,获得20
25秒前
打打应助Dave采纳,获得10
36秒前
47秒前
50秒前
ceeray23发布了新的文献求助20
51秒前
sh1ro发布了新的文献求助10
56秒前
nojego完成签到,获得积分10
1分钟前
脑洞疼应助科研通管家采纳,获得10
1分钟前
顾矜应助科研通管家采纳,获得10
1分钟前
wjx完成签到 ,获得积分10
1分钟前
John完成签到,获得积分10
1分钟前
顾矜应助ceeray23采纳,获得20
1分钟前
2分钟前
Able完成签到,获得积分10
2分钟前
我是笨蛋完成签到 ,获得积分10
2分钟前
ceeray23发布了新的文献求助20
2分钟前
Owen应助董可以采纳,获得10
2分钟前
酷酷妙梦完成签到,获得积分10
2分钟前
科研通AI2S应助彦嘉采纳,获得10
3分钟前
小二郎应助科研通管家采纳,获得10
3分钟前
hhh2018687完成签到,获得积分10
3分钟前
科研通AI2S应助ceeray23采纳,获得20
3分钟前
忘忧Aquarius完成签到,获得积分10
3分钟前
wujiwuhui完成签到 ,获得积分10
3分钟前
Lny发布了新的文献求助30
4分钟前
sh1ro完成签到,获得积分10
4分钟前
luang应助ceeray23采纳,获得40
4分钟前
4分钟前
ww完成签到,获得积分10
4分钟前
斯文败类应助ceeray23采纳,获得20
5分钟前
机智秋莲发布了新的文献求助20
5分钟前
ChatGPT完成签到,获得积分10
5分钟前
所所应助科研通管家采纳,获得10
5分钟前
5分钟前
5分钟前
ceeray23发布了新的文献求助20
5分钟前
海阔天空完成签到 ,获得积分10
5分钟前
zys发布了新的文献求助10
6分钟前
ffdhdh应助LYZSh采纳,获得10
6分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990543
求助须知:如何正确求助?哪些是违规求助? 3532220
关于积分的说明 11256532
捐赠科研通 3271057
什么是DOI,文献DOI怎么找? 1805207
邀请新用户注册赠送积分活动 882302
科研通“疑难数据库(出版商)”最低求助积分说明 809234