生物
仙台病毒
内胚层
胚芽层
胚状体
诱导多能干细胞
中胚层
外胚层
干细胞
尿
核型
细胞生物学
免疫学
内分泌学
遗传学
胚胎
胚胎干细胞
基因
胚胎发生
病毒
染色体
作者
Yangyang Liu,Xiaowei Li,Wanrong Fu,Mengduan Liu,Mengyu Wang,Liang Hu,Lu Wang,Xiaoyan Zhao,Zhongren Ding,Jianzeng Dong
标识
DOI:10.1016/j.scr.2021.102191
摘要
Urine cells (or renal tubular cells) can be isolated from human urine samples efficiently. This noninvasive and cost-effective method to collect biological sample provide us favorable access to donor cells from human. In the present study, we generate ZZUNEUi022-A, a urine cells-derived induced pluripotent stem cell (iPSC) line, from a 29-year-old healthy male via Sendai virus delivery system. ZZUNEUi022-A showed stable karyotype, and could differentiate into three germ layers (ectoderm, mesoderm, and endoderm) readily in an embryoid body formation model.
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