亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Risk factors for hepatic veno-occlusive disease caused by Gynura segetum: a retrospective study

医学 内科学 胃肠病学 肝性脑病 回顾性队列研究 肝静脉闭塞性疾病 经颈静脉肝内门体分流术 胆红素 存活率 肝病学 外科 比例危险模型 置信区间 疾病 肝硬化 门脉高压 造血干细胞移植
作者
Yan Wang,Dan Qiao,Ya Li,Feng Xu
出处
期刊:BMC Gastroenterology [BioMed Central]
卷期号:18 (1) 被引量:42
标识
DOI:10.1186/s12876-018-0879-7
摘要

Hepatic veno-occlusive disease (HVOD) caused by Gynura segetum has been increasingly reported in China in recent years. The aim of this retrospective study was to identify independent prognostic markers for survival in patients with Gynura segetum-induced HVOD and to evaluate the effect of anticoagulants and transjugular intrahepatic portosystemic shunt (TIPS) on survival rate. Clinical data including symptoms, signs, imaging characteristics, laboratory test results, results of liver tissue biopsies, type of treatment during follow-up and clinical outcomes were collected. Univariate, multivariate and time-dependent Cox regression analyses were performed. Survival rates were 91% (95% confidence interval [CI], 82–95%), 64% (95% CI, 53–69%) and 57% (95% CI, 51–65%) at 1, 3 and 60 months, respectively. Total bilirubin, albumin and hepatic encephalopathy were independent prognostic markers of survival. Anticoagulants were administered to 76% of the patients. Among 75 patients treated with anticoagulants, 49 patients (65.3%) were cured, whereas 26 patients (34.7%) died; the cure rate in anticoagulant-treated patients was higher than that of those not treated with anticoagulants (χ2 = 9.129, P = 0.004). Cure rate of the anticoagulation + TIPS treatment group was 64.3%, which was also higher than that of the non-anticoagulation group; however, this was not significantly different (χ2 = 3.938, P = 0.096). The presence of hepatic encephalopathy, serum bilirubin and albumin levels were major prognostic factors for Gynura segetum-induced HVOD. Anticoagulation therapy significantly increased the cure rate; however, TIPS treatment did not have a beneficial effect on the cure rate.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
2秒前
1分钟前
1分钟前
Tiger完成签到,获得积分10
1分钟前
1分钟前
2分钟前
Ma发布了新的文献求助10
2分钟前
2分钟前
2分钟前
科研通AI5应助Ma采纳,获得10
2分钟前
彼岸花开发布了新的文献求助10
2分钟前
3分钟前
易四夕发布了新的文献求助10
3分钟前
3分钟前
科研通AI2S应助科研通管家采纳,获得10
3分钟前
Ma发布了新的文献求助10
3分钟前
1234完成签到,获得积分10
3分钟前
岁和景明完成签到 ,获得积分10
4分钟前
科研通AI5应助Ma采纳,获得10
4分钟前
西蓝花香菜完成签到 ,获得积分10
4分钟前
5分钟前
5分钟前
5分钟前
科研通AI2S应助科研通管家采纳,获得10
5分钟前
科研通AI2S应助科研通管家采纳,获得10
5分钟前
Ma发布了新的文献求助10
5分钟前
5分钟前
科研通AI5应助Ma采纳,获得10
6分钟前
忧伤的绍辉完成签到 ,获得积分10
6分钟前
隐形曼青应助易四夕采纳,获得10
6分钟前
6分钟前
易四夕发布了新的文献求助10
6分钟前
7分钟前
7分钟前
Ma发布了新的文献求助10
7分钟前
7分钟前
随机子发布了新的文献求助10
7分钟前
7分钟前
Ava应助科研通管家采纳,获得10
7分钟前
科目三应助科研通管家采纳,获得10
7分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
A Preliminary Study on Correlation Between Independent Components of Facial Thermal Images and Subjective Assessment of Chronic Stress 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3968504
求助须知:如何正确求助?哪些是违规求助? 3513278
关于积分的说明 11167214
捐赠科研通 3248660
什么是DOI,文献DOI怎么找? 1794386
邀请新用户注册赠送积分活动 875030
科研通“疑难数据库(出版商)”最低求助积分说明 804638