Effects of Patisiran, an RNA Interference Therapeutic, on Cardiac Parameters in Patients With Hereditary Transthyretin-Mediated Amyloidosis
内科学
淀粉样蛋白(真菌学)
心力衰竭
核糖核酸
作者
Scott D. Solomon,David Adams,Arnt V. Kristen,Martha Grogan,Alejandra González-Duarte,Mathew S. Maurer,Giampaolo Merlini,Thibaud Damy,Michel Slama,Thomas H. Brannagan,Angela Dispenzieri,John L. Berk,Amil M. Shah,Pushkal Garg,Akshay Vaishnaw,Verena Karsten,Jihong Chen,Jared Gollob,John Vest,Ole B. Suhr
Background: Hereditary transthyretin-mediated (hATTR) amyloidosis is a rapidly progressive, multisystem disease that presents with cardiomyopathy or polyneuropathy. The APOLLO study assessed the ef ...