胶质瘤
纳米医学
聚合物
纳米技术
材料科学
甲基丙烯酸酯
生物分子
化学
生物物理学
癌症研究
医学
纳米颗粒
生物
聚合
复合材料
作者
Jia Guo,Zheng Yao,Feiyu Zhang,Feiyu Zhang
出处
期刊:Anti-cancer Agents in Medicinal Chemistry
[Bentham Science]
日期:2023-07-01
卷期号:23 (11): 1284-1297
被引量:1
标识
DOI:10.2174/1871520623666230222142825
摘要
Glioma is a serious life-threatening disease, and traditional treatments have little effect. In recent decades, polymer materials have been developed for the treatment of glioma as a new research area. The ability to target reactive polymeric carriers is important for treating glioma. Polymer materials have good designability and expansibility. They respond to different stimuli, leading to a change in the macroscopic properties of materials. Sensitive polymer carriers respond to biological stimuli (pH, oxidative stress, enzyme, temperature, ions and nucleic acids) and the tumour microenvironment. They can be used as intelligent polymer carriers to transport chemotherapy and imaging drugs for glioma treatment. The ability of these polymer carriers to control the release of molecules at tumour-specific sites has aroused great interest. This review summarizes current research on sensitive polymer-carriers for glioma treatment over the past decade, focusing on their clinical application prospects. Finally, future applications of polymer carriers in nanomedicine are reviewed.
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