氟罗沙星
抗菌剂
溶解度
盐(化学)
化学
酒石酸
色谱法
有机化学
生物化学
氧氟沙星
抗生素
环丙沙星
柠檬酸
作者
Lixin Liu,Yuning Wang,Jiuyi Sun,Yunan Zhang,Xiangyu Zhang,Lili Wu,Yingli Liu,Xuan Zhang,Yidi Xia,Qiumei Zhang,Ning Gao
标识
DOI:10.1016/j.ejpb.2024.114464
摘要
To improve the solubility of the fluoroquinolone drug fleroxacin (FL), based on the previous experience of our research group in synthesizing co-crystals/salts of quinolone drugs to improve the physicochemical properties of drugs, Fleroxacin-D-tartaric acid dihydrate salt (FL-D-TT, C
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