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医学
威尼斯人
弥漫性大B细胞淋巴瘤
美罗华
淋巴瘤
内科学
白血病
慢性淋巴细胞白血病
作者
Alessandra Tedeschi,Anna Maria Frustaci,Adalgisa Condoluci,Marta Coscia,Roberto Chiarle,Pier Luigi Zinzani,Marina Motta,Gianluca Gaïdano,Giulia Quaresmini,Lydia Scarfò,Gioacchino Catania,Marina Deodato,Rebecca Jones,Valentina Tabanelli,Valentina Griggio,Georg Stüssi,Angelica Calleri,Katia Pini,Roberto Cairoli,Thorsten Zenz
出处
期刊：Lancet Oncology
[Elsevier BV]
日期：2024-09-10
卷期号：25 (10): 1298-1309
被引量：8
标识
DOI：10.1016/s1470-2045(24)00396-6
摘要
The diffuse large B-cell lymphoma (DLBCL) variant of Richter transformation (DLBCL-RT) is typically chemoresistant with poor prognosis. Aiming to explore a chemotherapy-free treatment combination that triggers anti-tumour immune responses, we conducted a phase 2 study of atezolizumab (a PD-L1 inhibitor) in combination with venetoclax and obinutuzumab in patients with DLBCL-RT.
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