哈卡特
传统医学
夹竹桃科
银屑病
药用植物
植物
生物
医学
免疫学
细胞培养
遗传学
作者
Mukti Ojha,Nilanshu Manocha,Alka Madaan,N. Gupta,Saurabh Khurana,Anika Chaudhary,Arun Kumar Sharma,G. Karthikeyan,Devinder Toor
标识
DOI:10.1016/j.jep.2024.118596
摘要
Psoriasis, a widespread skin condition impacting over 100 million individuals globally, is characterised by uncontrolled hyperproliferation of keratinocytes, abnormal apoptosis, and excessive secretion of inflammatory cytokines and angiogenic factors. Traditional use of Alstonia scholaris (L.) R.Br., Wrightia tinctoria (Roxb.) R.Br. and Solanum xanthocarpum Schrad. & Wendl. in Ayurveda and Siddha medicinal systems have shown promising anti-inflammatory and wound-healing properties. However, underlying mechanisms of their phytoactivity in addressing psoriasis-like skin inflammation on human keratinocytes remain largely unexplored.
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