Scalable Lentiviral Vector Production Using Stable HEK293SF Producer Cell Lines

生物 载体(分子生物学) 可扩展性 生产(经济) 病毒载体 计算生物学 细胞培养 病毒学 细胞生物学 计算机科学 遗传学 重组DNA 基因 操作系统 宏观经济学 经济
作者
Aziza Manceur,Howard S. Kim,Vanja Misic,Nadejda Andreev,July Dorion-Thibaudeau,Stéphane Lanthier,Alice Bernier,Sonia Tremblay,Anne-Marie Gélinas,Sophie Broussau,Rénald Gilbert,Sven Ansorge
出处
期刊:Human Gene Therapy Methods [Mary Ann Liebert]
卷期号:28 (6): 330-339 被引量:92
标识
DOI:10.1089/hgtb.2017.086
摘要

Human Gene Therapy MethodsVol. 28, No. 6 Research ArticlesOpen AccessScalable Lentiviral Vector Production Using Stable HEK293SF Producer Cell LinesAziza P. Manceur, Howard Kim, Vanja Misic, Nadejda Andreev, July Dorion-Thibaudeau, Stéphane Lanthier, Alice Bernier, Sonia Tremblay, Anne-Marie Gélinas, Sophie Broussau, Rénald Gilbert, and Sven AnsorgeAziza P. ManceurHuman Health Therapeutics, National Research Council Canada, Montreal, CanadaSearch for more papers by this author, Howard KimBridGE, Centre for Commercialization of Regenerative Medicine, Toronto, Canada.Search for more papers by this author, Vanja MisicBridGE, Centre for Commercialization of Regenerative Medicine, Toronto, Canada.Search for more papers by this author, Nadejda AndreevBridGE, Centre for Commercialization of Regenerative Medicine, Toronto, Canada.Search for more papers by this author, July Dorion-ThibaudeauHuman Health Therapeutics, National Research Council Canada, Montreal, CanadaSearch for more papers by this author, Stéphane LanthierHuman Health Therapeutics, National Research Council Canada, Montreal, CanadaSearch for more papers by this author, Alice BernierHuman Health Therapeutics, National Research Council Canada, Montreal, CanadaSearch for more papers by this author, Sonia TremblayHuman Health Therapeutics, National Research Council Canada, Montreal, CanadaSearch for more papers by this author, Anne-Marie GélinasHuman Health Therapeutics, National Research Council Canada, Montreal, CanadaSearch for more papers by this author, Sophie BroussauHuman Health Therapeutics, National Research Council Canada, Montreal, CanadaSearch for more papers by this author, Rénald GilbertHuman Health Therapeutics, National Research Council Canada, Montreal, CanadaSearch for more papers by this author, and Sven AnsorgeHuman Health Therapeutics, National Research Council Canada, Montreal, CanadaSearch for more papers by this authorPublished Online:1 Dec 2017https://doi.org/10.1089/hgtb.2017.086AboutSectionsView articleSupplemental MaterialPDF/EPUBView Supplemental Data Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail View articleFiguresReferencesRelatedDetailsCited byPackaging cells for lentiviral vectors generated using the cumate and coumermycin 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Hurdles and Challenges in Scaling Up Manufacture19 June 2019Transient Lentiviral Vector Production Using a Packed-Bed Bioreactor System Alexandra McCarron, Martin Donnelley, Chantelle McIntyre, and David Parsons13 June 2019 | Human Gene Therapy Methods, Vol. 30, No. 3RNA Viruses as Tools in Gene Therapy and Vaccine Development1 March 2019 | Genes, Vol. 10, No. 3Optimization of production of vesicular stomatitis virus (VSV) in suspension serum-free culture medium at high cell densityJournal of Biotechnology, Vol. 289New technologies in gene therapy for inducing immune tolerance in hemophilia A3 November 2018 | Expert Review of Clinical Immunology, Vol. 14, No. 12Continuous manufacturing of viral particlesCurrent Opinion in Chemical Engineering, Vol. 22 Volume 28Issue 6Dec 2017 InformationCopyright 2017, Mary Ann Liebert, Inc.To cite this article:Aziza P. Manceur, Howard Kim, Vanja Misic, Nadejda Andreev, July Dorion-Thibaudeau, Stéphane Lanthier, Alice Bernier, Sonia Tremblay, Anne-Marie Gélinas, Sophie Broussau, Rénald Gilbert, and Sven Ansorge.Scalable Lentiviral Vector Production Using Stable HEK293SF Producer Cell Lines.Human Gene Therapy Methods.Dec 2017.330-339.http://doi.org/10.1089/hgtb.2017.086creative commons licensePublished in Volume: 28 Issue 6: December 1, 2017Online Ahead of Print:November 21, 2017Online Ahead of Editing: August 21, 2017Keywordslentiviral vectorstable producerHEK293SFperfusionbioprocessingPDF download
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