加压素
受体
催产素
加压素受体
中枢神经系统
神经科学
神经肽
催产素受体
生物
激素
内分泌学
内科学
医学
敌手
作者
E Tribollet,Claude Barberis
出处
期刊:Critical Reviews in Neurobiology
[Begell House Inc.]
日期:1996-01-01
卷期号:10 (1): 119-154
被引量:399
标识
DOI:10.1615/critrevneurobiol.v10.i1.60
摘要
This review concentrates on the pharmacological properties and the regional distribution of the arginine vasopressin (AVP) and oxytocin (OT) receptors that are present in the central nervous system. Of particular interest are the kinetics and the pharmacological profiles of these receptors that resemble those present at the periphery. However, their transduction mechanisms need to be further investigated. This should be rendered easier by molecular biology technology. The current knowledge of the anatomical distribution of AVP and OT receptors in the brain is reviewed. Also of great interest for double labeling studies will be the receptor antibodies, now being developed. The existence of additional receptors (AVP4-9) is examined, and aspects of the regulation of the receptors' expression in relation to the age, the species, and the hormonal status or following injury are also discussed.
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