基础(医学)
生物
抗氧化剂
免疫系统
舌头
脂质代谢
内科学
消化(炼金术)
新陈代谢
内分泌学
抗氧化能力
食品科学
生物化学
医学
免疫学
化学
病理
色谱法
胰岛素
作者
Shengpeng Wang,Wei Zhang,Aizhi Cao,Zhongchao Pan,Tailiang Liu
标识
DOI:10.3389/fmars.2022.899768
摘要
A 10-week feeding trial was conducted to investigate the beneficial effects of bile acids (BAs) on hepatic health status in tongue sole ( Cynoglossus semilaevis ). Three experimental diets were prepared with different levels of BA inclusion in the commercial basal diet: control group (CT: 0 mg/kg basal diet), low-level group (BA1: 300 mg/kg basal diet), and high-level group (900 mg/kg basal diet). At the end of the feeding trial, growth performance and survival rate were measured, as well as numerous physiological and biochemical parameters of the liver, including four hepatic function indices, five antioxidant indices, five lipid metabolism parameters, and three digestive enzyme activities. Moreover, the mRNA expression levels of three growth-related genes and three immune-related genes in the liver were assayed. Results showed that growth performance and survival were substantially improved in both low- and high-level BA inclusive groups. Further, the tested liver physiological and biochemical parameters combined with the quantitative real-time PCR results revealed enhanced antioxidant capacity, energy metabolism, digestive ability, and immune response. Finally, these findings provide a wider spectrum of the beneficial effects of dietary BAs on liver health in tongue sole.
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