[Statin-related drug-induced liver injury].

Statins are a kind of prescription drug that is widely used to treat hyperlipidemia, coronary artery disease, and other atherosclerotic diseases. A common side effect of statin use is a mild rise in liver aminotransferases, which occurs in less than 3% of patients. Statin-related liver injury is most commonly caused by atorvastatin and simvastatin, but severe liver injury is uncommon. Therefore, understanding and evaluating hepatotoxicity and weighing the benefits and risks is of great significance to better realize the protective effect of statins.他汀类药物是一类广泛用于治疗高脂血症、冠状动脉疾病和其他动脉粥样硬化疾病的处方药物。使用他汀类药物在肝脏常见的不良反应表现为转氨酶轻度升高，发生率低于3%。他汀类药物相关肝损伤最常由阿托伐他汀和辛伐他汀引起，但严重的肝损伤并不常见。认识和评价他汀类药物的肝毒性，权衡他汀类药物的获益和风险，对更好实现他汀类药物的保护作用具有重要意义。.