氨
过渡金属
水溶液
化学
分子
转化(遗传学)
腈
组合化学
有机化学
催化作用
生物化学
基因
作者
Jin Wang,Xiao‐Qin Yang,Na Li,Li.‐Li Wang
标识
DOI:10.1002/slct.202203982
摘要
Abstract A green and general method for the direct transformation of aldehydes to nitriles was developed. This method features a broad scope of substrates including aromatic, heterocyclic, and aliphatic aldehydes, by using I 2 /NH 4 Br in aqueous ammonia. Readily available aldehydes can be smoothly converted to corresponding nitriles in one‐step under open air at room temperature for 1–12 hours. This protocol is transition‐metal‐free and could be applied for the synthesis of various key cyano (CN)‐containing molecules.
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