Two new acylated flavonoid glycosides from Morina nepalensis var. alba Hand.‐Mazz.

Abstract From the whole plant of Morina nepalensis var. alba Hand.‐Mazz., two new acylated flavonoid glycosides ( 1 and 2 ), together with four known flavonoid glycosides ( 3–6 ), were isolated. Their structures were determined to be quercetin 3‐ O ‐[2″′‐ O ‐( E )‐caffeoyl]‐α‐ L ‐arabinopyranosyl‐(1→6)‐β‐ D ‐galactopyranoside (monepalin A, 1 ), quercetin 3‐ O ‐[2″′‐ O ‐( E )‐caffeoyl]‐α‐ L ‐arabinopyranosyl‐(1→6)‐β‐ D ‐glucopyranoside (monepalin B, 2 ), quercetin 3‐ O ‐α‐ L ‐arabinopyranosyl‐(1→6)‐β‐ D ‐galactopyranoside (rumarin, 3 ), quercetin 3‐ O ‐β‐ D ‐galactopyranoside ( 4 ), quercetin 3‐ O ‐β‐ D ‐glucopyranoside ( 5 ) and apigenin 4 ′ ‐ O ‐β‐ D ‐glucopyranoside ( 6 ). Their structures were determined on the basis of chemical and spectroscopic evidence. Complete assignments of the 1 H and 13 C NMR spectra of all compounds were achieved from the 2D NMR spectra, including H–H COSY, HMQC, HMBC and 2D HMQC‐TOCSY spectra. Copyright © 2002 John Wiley & Sons, Ltd.