Synthesis of 3‐Organoselenyl‐2H‐Coumarins from Propargylic Aryl Ethers via Oxidative Radical Cyclization

Abstract A metal‐free oxidative radical cyclization/selenylation of propargylic aryl ethers with diaryl diselenides was developed. This protocol provided an alternative method to synthesize 3‐organoselenyl‐2 H ‐coumarins via the formation of C−Se bond, C−C bond, and C=O bond in one step. Moreover, a broad range of functional groups (such as halogen, aldehyde, ketone, cyano, and nitro group) were tolerated. magnified image