神经科学
星形胶质细胞
纹状体
中棘神经元
生物神经网络
神经元
生物
脑功能
功能(生物学)
心理学
中枢神经系统
多巴胺
细胞生物学
标识
DOI:10.1016/j.tins.2019.06.003
摘要
The physiological functions of astrocytes within neural circuits remain incompletely understood. There has been progress in this regard from recent work on striatal astrocytes, where detailed studies are emerging. In this review, findings on striatal astrocyte identity, form, and function, are summarized with a focus on how astrocytes regulate striatal neurons, circuits, and behavior. Specific features of striatal astrocytes are highlighted to illustrate how they may be specialized to regulate medium spiny neurons (MSNs) by responding to, and altering, excitation and inhibition. Further experiments should reveal additional mechanisms for astrocyte-neuron interactions in the striatum and potentially reveal insights into the functions of astrocytes in neural circuits more generally.
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