Spinal cord regeneration in zebrafish

Neuroregeneration Unlike humans, zebrafish can regenerate their spinal cord. Mokalled et al. identified a growth factor in zebrafish that helps this process (see the Perspective by Williams and He). The protein encoded by ctgfa ( connective tissue growth factor a ) is secreted after injury and encourages glial cells to form a bridge across the spinal lesion. Addition of this protein improved spinal cord repair in injured zebrafish. Science , this issue p. [630][1]; see also p. [544][2] [1]: /lookup/doi/10.1126/science.aaf2679 [2]: /lookup/doi/10.1126/science.aal2112