作者
Sven Francque,Pierre Bédossa,Vlad Ratziu,Quentin M. Anstee,Elisabetta Bugianesi,Arun J. Sanyal,Rohit Loomba,Stephen A. Harrison,R. Balabanska,Lyudmila Mateva,Nicolas Lanthier,Naim Alkhouri,Christophe Moreno,Jörn M. Schattenberg,Diana Stefanova-Petrova,Luisa Vonghia,Roman Rouzier,Maëva Guillaume,Alexander Hodge,Manuel Romero‐Gómez,Philippe Huot-Marchand,Martine Baudin,Marie‐Paule Richard,Jean‐Louis Abitbol,Pierre Broqua,Jean‐Louis Junien,Manal F. Abdelmalek
摘要
Management of nonalcoholic steatohepatitis (NASH) is an unmet clinical need. Lanifibranor is a pan-PPAR (peroxisome proliferator–activated receptor) agonist that modulates key metabolic, inflammatory, and fibrogenic pathways in the pathogenesis of NASH.