维甲酸
过氧化物还原蛋白
分化疗法
转录因子
细胞分化
急性早幼粒细胞白血病
细胞生物学
激酶
化学
癌症研究
生物
分子生物学
生物化学
过氧化物酶
酶
基因
作者
Chuanxu Liu,Qianqian Yin,Huchen Zhou,Yingli Wu,Jian‐Xin Pu,Li Xia,Wei Liu,Xin Huang,Tao Jiang,Mingxuan Wu,Licai He,Yaxue Zhao,Xiaolin Wang,Wei‐Lie Xiao,Hongzhuan Chen,Qian Zhao,Aiwu Zhou,Li‐Shun Wang,Han‐Dong Sun,Guo‐Qiang Chen
摘要
The diperpenoid adenanthin covalently modifies the resolving cysteine from peroxiredoxins to inhibit the reduction of hydrogen peroxide, a second messenger in cells, and thereby activates pathways that promote the differentiation of leukemia cells.
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