区域选择性
化学
高价分子
吡啶
二氯甲烷
碘
戒指(化学)
药物化学
有机化学
催化作用
溶剂
作者
Ping Yang,Mi Ting Tsai,Meng Han Tsai,Chi Wi Ong
标识
DOI:10.1002/asia.201403359
摘要
The C - H homocoupling of meta-hydroxypyridines with phenyliodine(III) diacetate (PIDA) was carried out in dichloromethane at room temperature in the presence of cesium carbonate. The coupling reaction is highly regioselective with respect to the hydroxy group at the pyridine ring. Comparative control experiments with meta-alkoxypyridine suggest that the meta-hydroxy group at the pyridine ring plays a key role during the homocoupling reaction.
科研通智能强力驱动
Strongly Powered by AbleSci AI