Prevention of Cardiovascular Disease — Don’t Stop Thinking about Tomorrow

Taking a long-term view of cardiovascular disease prevention is an attractive strategy since atherosclerosis begins early in life and progresses over decades. Lowering low-density lipoprotein (LDL) cholesterol levels and improving lifestyle habits are mainstay strategies for reducing the risk of cardiovascular disease.1 Moreover, emerging therapeutic targets include vascular inflammation as reflected by elevated levels of high-sensitivity C-reactive protein (CRP) and lipoprotein(a). Ridker et al. now report in the Journal the results of an examination of the long-term predictive value of a single baseline measurement of high-sensitivity CRP, LDL cholesterol, and lipoprotein(a) levels in nearly 28,000 healthy, female, U.S. health professionals . . .