Digging deep: microbial PFAS-degradation in landfill sediments

Per- and polyfluoroalkyl substances (PFAS) are detrimental to human and environmental health. Here, we discuss obstacles hindering PFAS biodegradation, addressing challenges from chemical and microbial ecotoxicological perspectives. We then highlight the unique eco-evolutionary landscapes of buried landfills and consider the importance of these underexplored xeno-ecological niches for promoting PFAS biodegradation.