遗传建筑学
错误发现率
生物
表达数量性状基因座
遗传学
全基因组关联研究
数量性状位点
表型
帕金森病
等位基因
疾病
多重比较问题
基因
医学
基因型
病理
单核苷酸多态性
统计
数学
作者
Dongrui Ma,Shuangjie Li,Jingjing Shi,Yuanyuan Liang,Zheng‐wei Hu,Xiaoyan Hao,Meng‐jie Li,Meng-Nan Guo,Chun‐yan Zuo,Wen-Kai Yu,Cheng‐yuan Mao,Mibo Tang,Chan Zhang,Yuming Xu,Jun Wu,Shilei Sun,Changhe Shi
摘要
We confirmed the polygenic overlap with mixed directions of allelic effects between PD and BSPs and identified multiple shared genomic loci and risk genes, which are likely related to immune-related biological processes. These findings provide insight into the complex genetic architecture associated with PD. © 2023 International Parkinson and Movement Disorder Society.
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