One-step synthesis of indole atropisomers with vicinal diaxes via Co-catalyzed C–H activation

In this issue of Chem Catalysis, Wencel-Delord, Ackermann, and colleagues disclosed an efficient one-step synthesis of novel indole atropisomers with vicinal C–C and C–N diaxes through C–H activation, exhibiting high diastereoselectivities and enantioselectivities by leveraging the earth-abundant cobalt catalyst and a finely tuned multi-substituted NHC ligand.