啮齿动物模型
啮齿动物
药理学
医学
主动脉瘤
化学
主动脉
内科学
生物
生态学
作者
Yongzhen Wei,Huan Jiang,Fengjuan Li,Chao Chai,XU Ya-ping,Mengmeng Xing,Weiliang Deng,He Wang,Yuexin Zhu,Sen Yang,Yongquan Yu,Wenming Wang,Yan Wei,Yu Guo,Jinwei Tian,Jie Du,Z. Guo,Yuan Wang,Qiang Zhao
出处
期刊：Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期：2024-05-01
卷期号：16 (745)
标识
DOI：10.1126/scitranslmed.adh1763
摘要
An abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. We identified plasma insulin-like growth factor 1 (IGF1) as an independent risk factor in patients with AAA by correlating plasma IGF1 with risk. Smooth muscle cell- or fibroblast-specific knockout of
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