Continuous design and technoeconomic assessment of commercial‐scale biorefinery processes for the production of succinic acid

Abstract Succinic acid is recognized as a key component in the production of various commercially important chemical commodities. Technical‐economic analysis can provide valuable insights into the feasibility of large‐scale biochemical production of succinic acid. In this study, the effects of scale on the design of a biorefinery using sugarcane bagasse were evaluated using a detailed process modeling methodology. Four processes were simulated and compared, three based on patents from biosuccinic acid (bio‐SA) manufacturing companies and one based on a process economic program report (PEP). This methodology allowed for the analysis of scale benefits for each technological route. A comprehensive economic evaluation was conducted by comparing the biochemical processes in terms of investment and production costs, as well as the minimum selling price (MSP) of bio‐SA. Results show that the MSP of more promising process designs ranged from 3105 to 2095 $ t −1 , which is compatible with the cost of petrochemical‐based succinic acid. Moreover, for capacities above 90 kt year −1 , the MSP remains virtually constant, and every process evaluated revealed a breakdown in the project economy of scale. A sensitivity and risk analysis was carried out to evaluate the impacts of several process parameters on the project's technoeconomic analysis, resulting in bio‐SA selling price and investment costs as parameters with the highest impact on economic viability.